Mal-PEG1-acid

Mal-PEG1-acid is is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product Specifications

CAS Number

[760952-64-5]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; PROTAC

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mal-peg1-acid.html

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)CCOCCN1C(C=CC1=O)=O

Molecular Formula

C9H11NO5

Molecular Weight

213.19

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.