HTRA1 Recombinant Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space.
Synonyms
ARMD7; CARASIL; High-temperature requirement A serine peptidase 1; HtrA; HtrA serine peptidase 1; HTRA1; IGFBP5 protease; ORF480; Protease serine 11 (IGF binding) ; protease serine 11; PRSS11; Serine protease 11; Serine protease HTRA1.
Gene ID
5654
Swiss Prot
Q92743
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human
Target
HTRA1
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic peptide derived from human Serine protease HTRA1
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5654
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