RIP2 Recombinant Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Serine/threonine/tyrosine-protein kinase that plays an essential role in modulation of innate and adaptive immune responses. Acts as a key effector of NOD1 and NOD2 signaling pathways: upon activation by bacterial peptidoglycans, NOD1 and NOD2 oligomerize and recruit RIPK2 via CARD-CARD domains, leading to the formation of RIPK2 filaments.
Synonyms
CARD carrying kinase; CARD3; CARDIAK; CCK; CLARP kinase; GIG30; Growth inhibiting gene 30; Receptor interacting protein 2; RICK; RIP 2; Ripk2; TNFRSF.
Gene ID
8767
Swiss Prot
O43353
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
RIP2
Clonality
Recombinant
Isotype
IgG
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from human RIP 2
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8767
Predicted Cross Reactivity
Rat
Curated Selection
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