RIP2 Recombinant Antibody, Cy3 Conjugated
Product Specifications
Background
Serine/threonine/tyrosine-protein kinase that plays an essential role in modulation of innate and adaptive immune responses. Acts as a key effector of NOD1 and NOD2 signaling pathways: upon activation by bacterial peptidoglycans, NOD1 and NOD2 oligomerize and recruit RIPK2 via CARD-CARD domains, leading to the formation of RIPK2 filaments.
Synonyms
CARD carrying kinase; CARD3; CARDIAK; CCK; CLARP kinase; GIG30; Growth inhibiting gene 30; Receptor interacting protein 2; RICK; RIP 2; Ripk2; TNFRSF.
Gene ID
8767
Swiss Prot
O43353
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
RIP2
Clonality
Recombinant
Isotype
IgG
Conjugation
Cy3
Source
KLH conjugated synthetic peptide derived from human RIP 2
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8767
Predicted Cross Reactivity
Rat
Curated Selection
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