HMGCL Recombinant Antibody, Cy7 Conjugated

Product Specifications

Background

Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S) -3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

Synonyms

HMG CoA lyase; HMGCL; Hydroxymethylglutaricaciduria; MS725.

Gene ID

3155

Swiss Prot

P35914

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

HMGCL

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from human HMGCL

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3155

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