HMGCL Recombinant Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S) -3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.
Synonyms
HMG CoA lyase; HMGCL; Hydroxymethylglutaricaciduria; MS725.
Gene ID
3155
Swiss Prot
P35914
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
HMGCL
Clonality
Recombinant
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human HMGCL
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3155
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