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Phospho-PBK (Thr9) Recombinant Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.

Synonyms

CT84; MAPKK like protein kinase; Nori3; PBK; PDZ binding kinas; Serine/threonine protein kinase; SPK; TOPK.

Gene ID

55872

Swiss Prot

Q96KB5

Modification Site

Thr9

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

PBK

Clonality

Recombinant

Isotype

IgG

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human PBK around the phosphorylation site of T9

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

55872

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