Phospho-Rb2 p130 (T986) Recombinant Antibody, Cy3 Conjugated

Product Specifications

Background

Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation.

Synonyms

130 kDa retinoblastoma associated protein; IB4; p130; PRB2; Rb2; Rbl2; RBR2; Retinoblastoma like 2; Retinoblastoma-related protein 2; RIC128.

Gene ID

5934

Swiss Prot

Q08999

Modification Site

Thr986

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

Rb2 p130

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human RBL2 around the phosphorylation site of T986

Applications

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5934

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