GLCNE Recombinant Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Bifunctional enzyme that possesses both UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activities, and serves as the initiator of the biosynthetic pathway leading to the production of N-acetylneuraminic acid (NeuAc), a critical precursor in the synthesis of sialic acids. By catalyzing this pivotal and rate-limiting step in sialic acid biosynthesis, this enzyme assumes a pivotal role in governing the regulation of cell surface sialylation.
Synonyms
DMRV; GNE; IBM2; ManAc kinase; Uae1; GLCNE.
Gene ID
10020
Swiss Prot
Q9Y223
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
GLCNE
Clonality
Recombinant
Isotype
IgG
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from human GNE
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10020
Available Sizes
Curated Selection
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