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GLCNE Recombinant Antibody, PE Conjugated

Product Specifications

Background

Bifunctional enzyme that possesses both UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activities, and serves as the initiator of the biosynthetic pathway leading to the production of N-acetylneuraminic acid (NeuAc), a critical precursor in the synthesis of sialic acids. By catalyzing this pivotal and rate-limiting step in sialic acid biosynthesis, this enzyme assumes a pivotal role in governing the regulation of cell surface sialylation.

Synonyms

DMRV; GNE; IBM2; ManAc kinase; Uae1; GLCNE.

Gene ID

10020

Swiss Prot

Q9Y223

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

GLCNE

Clonality

Recombinant

Isotype

IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human GNE

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10020

Available Sizes

Curated Selection

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