Phospho-MDM2 (Ser166) Recombinant Antibody, APC-Cy7 Conjugated

Product Specifications

Background

E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.

Synonyms

ACTFS; Hdm2; HDMX; MDM2; MDM2BP; MTBP.

Gene ID

4193

Swiss Prot

Q00987

Modification Site

Ser166

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

MDM2

Clonality

Recombinant

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from human MDM2 around the phosphorylation site of S166

Applications

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4193

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