RNF14 Recombinant Antibody, Cy7 Conjugated
Product Specifications
Background
E3 ubiquitin-protein ligase that plays a key role in the RNF14-RNF25 translation quality control pathway, a pathway that takes place when a ribosome has stalled during translation, and which promotes ubiquitination and degradation of translation factors on stalled ribosomes.Recruited to stalled ribosomes by the ribosome collision sensor GCN1 and mediates 'Lys-6'-linked ubiquitination of target proteins, leading to their degradation.
Synonyms
ARA54; HFB30; Rnf14; TRIAD2.
Gene ID
9604
Swiss Prot
Q9UBS8
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
RNF14
Clonality
Recombinant
Isotype
IgG
Conjugation
Cy7
Source
KLH conjugated synthetic peptide derived from human RNF14
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
743nm/767nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
9604
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