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RNF14 Recombinant Antibody, Cy3 Conjugated

Product Specifications

Background

E3 ubiquitin-protein ligase that plays a key role in the RNF14-RNF25 translation quality control pathway, a pathway that takes place when a ribosome has stalled during translation, and which promotes ubiquitination and degradation of translation factors on stalled ribosomes.Recruited to stalled ribosomes by the ribosome collision sensor GCN1 and mediates 'Lys-6'-linked ubiquitination of target proteins, leading to their degradation.

Synonyms

ARA54; HFB30; Rnf14; TRIAD2.

Gene ID

9604

Swiss Prot

Q9UBS8

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

RNF14

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human RNF14

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

9604

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