Phospho-EIF4B (Ser406) Recombinant Antibody, PE-Cy7 Conjugated
Product Specifications
Background
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Synonyms
EIF4B
Gene ID
1975
Swiss Prot
P23588
Modification Site
Ser406
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
EIF4B
Clonality
Recombinant
Isotype
IgG
Conjugation
PE-Cy7
Source
KLH conjugated synthetic peptide derived from human eIF4B around the phosphorylation site of S406
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1975
Curated Selection
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