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Phospho-EIF4B (Ser406) Recombinant Antibody, APC Conjugated

Product Specifications

Background

Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Synonyms

EIF4B

Gene ID

1975

Swiss Prot

P23588

Modification Site

Ser406

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

EIF4B

Clonality

Recombinant

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human eIF4B around the phosphorylation site of S406

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1975

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