UBA3 Recombinant Antibody, Biotin Conjugated
Product Specifications
Background
Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.
Synonyms
HUba3; NEDD8 activating enzyme E1C; uba3; UBE1C.
Gene ID
9039
Swiss Prot
Q8TBC4
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
UBA3
Clonality
Recombinant
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human UBA3
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
9039
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