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UBE2L3 Recombinant Antibody, PE-Cy7 Conjugated

Product Specifications

Background

Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PRKN, RNF31 and ARIH1, that function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination.

Synonyms

UBCE7; UbcH7; UbcM4; Ube2l3.

Gene ID

7332

Swiss Prot

P68036

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

UBE2L3

Clonality

Recombinant

Isotype

IgG

Conjugation

PE-Cy7

Source

KLH conjugated synthetic peptide derived from human UBE2L3

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7332

Available Sizes

Curated Selection

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