GRK6 Recombinant Antibody, AbBy Fluor™ 750 Conjugated
Selected Variant
bsm-62587R-BF750
Size: 100 µL
Product Specifications
Background
Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro) .
Synonyms
G protein coupled receptor kinase 6; G protein coupled receptor kinase GRK6; G protein-coupled receptor kinase 6; Gprk6; Grk6.
Gene ID
2870
Swiss Prot
P43250
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
GRK6
Clonality
Recombinant
Isotype
IgG
Conjugation
AbBy Fluor™ 750
Source
KLH conjugated synthetic peptide derived from human GRK6
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
749nm/775nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2870
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNCB0960-500 1x 500 µL
MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC472441-500 1x 500 µL
GATA-3 (Breast and Urothelial Marker) (GATA3/2441), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 