RPS6KA3 Recombinant Antibody, PE-Cy7 Conjugated
Product Specifications
Background
Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1.
Synonyms
CLS; HU2; HU3; Insulin stimulated protein kinase 1; ISPK1; MAP kinase activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK 1b; MAPKAPK1B; MRX19; p90 RSK2; p90 RSK3; p90RSK3; pp90RSK2; Ribosomal protein S6 kinase alpha 3; Ribosomal protein s6 kinase ii alpha 2; Ribosomal S6 kinase 2; Rps6ka3; RSK; RSK2; S6 kinase 2; S6K alpha3.
Gene ID
6197
Swiss Prot
P51812
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
RPS6KA3
Clonality
Recombinant
Isotype
IgG
Conjugation
PE-Cy7
Source
KLH conjugated synthetic peptide derived from human p90 S6K alpha 3
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6197
Curated Selection
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