RPS6KA3 Recombinant Antibody, Cy5.5 Conjugated
Product Specifications
Background
Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1.
Synonyms
CLS; HU2; HU3; Insulin stimulated protein kinase 1; ISPK1; MAP kinase activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK 1b; MAPKAPK1B; MRX19; p90 RSK2; p90 RSK3; p90RSK3; pp90RSK2; Ribosomal protein S6 kinase alpha 3; Ribosomal protein s6 kinase ii alpha 2; Ribosomal S6 kinase 2; Rps6ka3; RSK; RSK2; S6 kinase 2; S6K alpha3.
Gene ID
6197
Swiss Prot
P51812
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
RPS6KA3
Clonality
Recombinant
Isotype
IgG
Conjugation
Cy5.5
Source
KLH conjugated synthetic peptide derived from human p90 S6K alpha 3
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
675nm/694nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6197
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