SCIN Recombinant Antibody, RBITC Conjugated
Product Specifications
Background
Ca2+-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane.Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate.In vitro, also has barbed end capping and nucleating activities in the presence of Ca2+. Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles.
Synonyms
Adseverin; Scin; Scinderin.
Gene ID
85477
Swiss Prot
Q9Y6U3
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse, Rat
Target
SCIN
Clonality
Recombinant
Isotype
IgG
Conjugation
RBITC
Source
KLH conjugated synthetic peptide derived from human Scinderin
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
85477
Predicted Cross Reactivity
Human
Curated Selection
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