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SCIN Recombinant Antibody, PE-Cy7 Conjugated

Product Specifications

Background

Ca2+-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane.Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate.In vitro, also has barbed end capping and nucleating activities in the presence of Ca2+. Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles.

Synonyms

Adseverin; Scin; Scinderin.

Gene ID

85477

Swiss Prot

Q9Y6U3

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Mouse, Rat

Target

SCIN

Clonality

Recombinant

Isotype

IgG

Conjugation

PE-Cy7

Source

KLH conjugated synthetic peptide derived from human Scinderin

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

85477

Predicted Cross Reactivity

Human

Curated Selection

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