RGMA Recombinant Antibody, PerCP Conjugated
Product Specifications
Background
Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition.
Synonyms
Repulsive guidance molecule A; RGM; RGM domain family member A; RGMA.
Gene ID
56963
Swiss Prot
Q96B86
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
RGMA
Clonality
Recombinant
Isotype
IgG
Conjugation
PerCP
Source
KLH conjugated synthetic peptide derived from human Repulsive guidance molecule A
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
482nm/677nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
56963
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15361980 1 Vial
Lentiviral human TNFRSF1A sgRNA gene knockout kit - Lentiviral human TNFRSF1A sgRNA gene knockout kit (25)
Ask
View Details 
040377-AP 200 µL
PQLC2, CT (PQLC2, PQ-loop repeat-containing protein 2) (AP) discontinued
Ask
View Details 243666-ML550 100 µL
AXIN2 (Axin 2, AXIL, DKFZp781B0869, MGC10366, MGC126582) (MaxLight 550)
Ask
View Details MBS6338527-01 0.2 mL
PTEN, Phosphorylated (S294) (PTEN, MMAC1, TEP1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog) (FITC)
Ask
View Details MBS6338527-02 5x 0.2 mL
PTEN, Phosphorylated (S294) (PTEN, MMAC1, TEP1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog) (FITC)
Ask
View Details