BRMS1 Recombinant Antibody, FITC Conjugated

Product Specifications

Background

Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.

Synonyms

BRMS1

Gene ID

25855

Swiss Prot

Q9HCU9

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

BRMS1

Clonality

Recombinant

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human BRMS1

Applications

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

IF (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

25855

Available Sizes

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