NPC1 Recombinant Antibody, RBITC Conjugated

Product Specifications

Background

Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment.Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1.

Synonyms

Niemann Pick C1 protein precursor; NPC; NPC1.

Gene ID

4864

Swiss Prot

O15118

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

NPC1

Clonality

Recombinant

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human Niemann pick C1

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4864

Available Sizes

Curated Selection

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