Caspase 5 Recombinant Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

Thiol protease that acts as a mediator of programmed cell death.Initiates pyroptosis, a programmed lytic cell death pathway through cleavage of Gasdermin-D (GSDMD) : cleavage releases the N-terminal gasdermin moiety (Gasdermin-D, N-terminal) that binds to membranes and forms pores, triggering pyroptosis.

Synonyms

CASP5; Apoptosis related cysteine protease; CASP-5; Caspase-5 subunit p10; Protease ICH-3; TY protease.

Gene ID

838

Swiss Prot

P51878

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

Caspase 5

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human Caspase 5

Applications

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

838

Available Sizes

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