Caspase 5 Recombinant Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Thiol protease that acts as a mediator of programmed cell death.Initiates pyroptosis, a programmed lytic cell death pathway through cleavage of Gasdermin-D (GSDMD) : cleavage releases the N-terminal gasdermin moiety (Gasdermin-D, N-terminal) that binds to membranes and forms pores, triggering pyroptosis.
Synonyms
CASP5; Apoptosis related cysteine protease; CASP-5; Caspase-5 subunit p10; Protease ICH-3; TY protease.
Gene ID
838
Swiss Prot
P51878
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
Caspase 5
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic peptide derived from human Caspase 5
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
838
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