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Crotonyl-Histone H2B type 2E (Lys12) Recombinant Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms

Histone H2B type 1-H; Histone H2B.j; H2B/j; HIST1H2BH; H2BFJ.

Gene ID

8349

Swiss Prot

Q16778

Modification Site

Lys12

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Crotonyl-Histone H2B type 2E (Lys12)

Clonality

Recombinant

Isotype

IgG

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human Histone H2B type 2E around the crotonylation site of K12

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Crotonylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8349

Available Sizes

Curated Selection

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