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PAG1 Recombinant Antibody, PerCP Conjugated

Product Specifications

Background

Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor) -mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

Synonyms

CBP; Csk binding protein; PAG; PAG1.

Gene ID

55824

Swiss Prot

Q9NWQ8

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

PAG1

Clonality

Recombinant

Isotype

IgG

Conjugation

PerCP

Source

KLH conjugated synthetic peptide derived from human PAG1

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bsm-62406R-PerCP

Gene ID URL

55824

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