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ERCC8 Recombinant Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX (ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair.

Synonyms

CKN1; CSA; ERCC8.

Gene ID

1161

Swiss Prot

Q13216

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

ERCC8

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 594

Source

KLH conjugated synthetic peptide derived from human ERCC8

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1161

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