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DOCK2 Recombinant Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

Synonyms

DOCK 2; IMD40.

Gene ID

1794

Swiss Prot

Q92608

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

DOCK2

Clonality

Recombinant

Isotype

IgG

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from human Dedicator of cytokinesis protein 2

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1794

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