DOCK2 Recombinant Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
Synonyms
DOCK 2; IMD40.
Gene ID
1794
Swiss Prot
Q92608
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
DOCK2
Clonality
Recombinant
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human Dedicator of cytokinesis protein 2
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1794
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