MonoMethyl-Histone H2B type 2E (Arg80) Recombinant Antibody, Cy5 Conjugated

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms

H2B; H2BQ; GL105; H2B.1; H2BFQ; H2BGL105; H2R79me1.

Gene ID

8349

Swiss Prot

Q16778

Modification Site

Srg80

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

Histone H2B type 2E

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human Histone H2B type 2E around the methylation site of R80

Applications

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Methylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8349

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