ARTS1 Recombinant Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus.
Synonyms
ALAP; Aminopeptidase PILS; APPILS; Arts1; Endoplasmic reticulum aminopeptidase 1; ERAAP; ERAAP1; Erap1; PILSA; PILSAP.
Gene ID
51752
Swiss Prot
Q9NZ08
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
ARTS1
Clonality
Recombinant
Isotype
IgG
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from human ERAP1
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
51752
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