PA26 Recombinant Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its interaction with GATOR2 thereby activating the TORC1 signaling pathway.

Synonyms

PA26; sesn1; SEST1; sestrin 1.

Gene ID

27244

Swiss Prot

Q9Y6P5

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

PA26

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 680

Source

KLH conjugated synthetic peptide derived from human Sestrin 1

Applications

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

27244

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

LS080176-20ug 20 µg

SPSB1 (NM_025106) Human Over-expression Lysate

Ask

View Details

mm30197 500 ng

LentimiRa-Off-mmu-miR-1894-3p Vector

Ask

View Details

NBP2-12235FR 0.1 mL

Mouse Monoclonal CXCL8/IL-8 Antibody (MM0219-7F11) [DyLight 680]

Ask

View Details

bs-4308R-BF350-01 20 µL

Phospho-IRE1a (Ser 726) Polyclonal Antibody, AbBy Fluor™ 350 Conjugated

Ask

View Details

bs-4308R-BF350-02 100 µL

Phospho-IRE1a (Ser 726) Polyclonal Antibody, AbBy Fluor™ 350 Conjugated

Ask

View Details

GTR15380206 1 Vial

Lentiviral human ACAD9 sgRNA gene knockout kit - Lentiviral human ACAD9 sgRNA gene knockout kit (100)

Ask

View Details