Phospho-GluR1 (Ser831) Recombinant Antibody, PE-Cy7 Conjugated

Product Specifications

Background

AMPA- (ŚÁ-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainate-, and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4), which assemble as homo- or hetero-tetramers to mediate the majority of fast excitatory transmissions in the central nervous system. AMPARs are implicated in synapse formation, stabilization, and plasticity.

Synonyms

GLUR 1; GLUR A; AMPA 1; AMPA selective glutamate receptor 1; GluA1; GLUH1; GluR K1; GLUR1; GLURA; GluRK1; Glutamate receptor 1; Glutamate receptor ionotropic AMPA 1; Glutamate receptor ionotropic; Glutamate receptor, ionotropic, AMPA 1; Gria1; HBGR1.

Gene ID

2890

Swiss Prot

P42261

Modification Site

Ser831

Cellular Locus

Extracellular, Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

GluR1

Clonality

Recombinant

Isotype

IgG

Conjugation

PE-Cy7

Source

KLH conjugated synthetic peptide derived from human GluR1 around the phosphorylation site of S831

Applications

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2890

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