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Phospho-GluR1 (Ser831) Recombinant Antibody, Cy5 Conjugated

Product Specifications

Background

AMPA- (ŚÁ-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainate-, and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4), which assemble as homo- or hetero-tetramers to mediate the majority of fast excitatory transmissions in the central nervous system. AMPARs are implicated in synapse formation, stabilization, and plasticity.

Synonyms

GLUR 1; GLUR A; AMPA 1; AMPA selective glutamate receptor 1; GluA1; GLUH1; GluR K1; GLUR1; GLURA; GluRK1; Glutamate receptor 1; Glutamate receptor ionotropic AMPA 1; Glutamate receptor ionotropic; Glutamate receptor, ionotropic, AMPA 1; Gria1; HBGR1.

Gene ID

2890

Swiss Prot

P42261

Modification Site

Ser831

Cellular Locus

Extracellular, Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

GluR1

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human GluR1 around the phosphorylation site of S831

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2890

Curated Selection

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