Phospho-GluR1 (Ser831) Recombinant Antibody, Cy3 Conjugated
Product Specifications
Background
AMPA- (ŚÁ-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainate-, and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4), which assemble as homo- or hetero-tetramers to mediate the majority of fast excitatory transmissions in the central nervous system. AMPARs are implicated in synapse formation, stabilization, and plasticity.
Synonyms
GLUR 1; GLUR A; AMPA 1; AMPA selective glutamate receptor 1; GluA1; GLUH1; GluR K1; GLUR1; GLURA; GluRK1; Glutamate receptor 1; Glutamate receptor ionotropic AMPA 1; Glutamate receptor ionotropic; Glutamate receptor, ionotropic, AMPA 1; Gria1; HBGR1.
Gene ID
2890
Swiss Prot
P42261
Modification Site
Ser831
Cellular Locus
Extracellular, Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
GluR1
Clonality
Recombinant
Isotype
IgG
Conjugation
Cy3
Source
KLH conjugated synthetic peptide derived from human GluR1 around the phosphorylation site of S831
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2890
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