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TMPRSS2 Recombinant Antibody, PerCP-Cy5.5 Conjugated

Product Specifications

Background

Plasma membrane-anchored serine protease that cleaves at arginine residues.Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. (Microbial infection) Facilitates human coronaviruses SARS-CoV and SARS-CoV-2 infections via two independent mechanisms, proteolytic cleavage of ACE2 receptor which promotes viral uptake, and cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry.

Synonyms

Epitheliasin; PRSS10; TMPRSS2.

Gene ID

7113

Swiss Prot

O15393

Cellular Locus

Secreted, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

TMPRSS2

Clonality

Recombinant

Isotype

IgG

Conjugation

PerCP-Cy5.5

Source

KLH conjugated synthetic peptide derived from human TMPRSS2

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

482nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7113

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