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PRKRA Recombinant Antibody, APC Conjugated

Product Specifications

Background

Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing.

Synonyms

RAX; PACT; DYT16; HSD14.

Gene ID

8575

Swiss Prot

O75569

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

PRKRA

Clonality

Recombinant

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human PRKRA

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8575

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