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PAF1 Recombinant Antibody, Cy3 Conjugated

Product Specifications

Background

Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both independently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1.

Synonyms

HPAF1; PAF1; PD2.

Gene ID

54623

Swiss Prot

Q8N7H5

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

PAF1

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human PAF1

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

54623

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