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VPS11 Recombinant Antibody, FITC Conjugated

Product Specifications

Background

Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion.

Synonyms

END1; hVPS11; PEP5; PP3476; RNF108; vps11.

Gene ID

55823

Swiss Prot

Q9H270

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

VPS11

Clonality

Recombinant

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human VPS11

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

55823

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