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VPS11 Recombinant Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion.

Synonyms

END1; hVPS11; PEP5; PP3476; RNF108; vps11.

Gene ID

55823

Swiss Prot

Q9H270

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

VPS11

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human VPS11

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

55823

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