RING1 Recombinant Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.

Synonyms

Ring1A; Ring1; RING1A; Rnf1.

Gene ID

6015

Swiss Prot

Q06587

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

RING1

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic peptide derived from human RING1

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6015

Available Sizes

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