SorLA Recombinant Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Sorting receptor that directs several proteins to their correct location within the cell (Probable) . Along with AP-1 complex, involved Golgi apparatus - endosome sorting.Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated.

Synonyms

Gp250; LR11; LRP9; SORL1; SorLA 1; SorLA.

Gene ID

6653

Swiss Prot

Q92673

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

SorLA

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic peptide derived from human Sortilin related receptor

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6653

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