EBF1 Recombinant Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Key pioneer transcription factor of B-cell specification and commitment.Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage.
Synonyms
COE1; EBF; Ebf1; O/E 1; OE1; OLF1.
Gene ID
1879
Swiss Prot
Q9UH73
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
EBF1
Clonality
Recombinant
Isotype
IgG
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from human COE1
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1879
Curated Selection
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