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EBF1 Recombinant Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Key pioneer transcription factor of B-cell specification and commitment.Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage.

Synonyms

COE1; EBF; Ebf1; O/E 1; OE1; OLF1.

Gene ID

1879

Swiss Prot

Q9UH73

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

EBF1

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human COE1

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1879

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