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EBF1 Recombinant Antibody, APC Conjugated

Product Specifications

Background

Key pioneer transcription factor of B-cell specification and commitment.Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage.

Synonyms

COE1; EBF; Ebf1; O/E 1; OE1; OLF1.

Gene ID

1879

Swiss Prot

Q9UH73

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

EBF1

Clonality

Recombinant

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human COE1

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1879

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