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HBEGF Recombinant Antibody, HRP Conjugated

Product Specifications

Background

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

Synonyms

DTR; DTS; DTSF; HB-EGF; HBEGF; HEGFL.

Gene ID

1839

Swiss Prot

Q99075

Cellular Locus

Secreted, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Target

HBEGF

Clonality

Recombinant

Isotype

IgG

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human HB EGF

Applications

WB

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1839

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