Niemann Pick C1 Like 1 Recombinant Antibody, PerCP Conjugated

Product Specifications

Background

Plays a major role in cholesterol homeostasis.Critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte.Involved in plant sterol absorption, it transports sitosterol, although at lower rates than cholesterol.Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption and is approved for the treatment of hypercholesterolemia.

Synonyms

NPC1 LIKE 1; NPC1L1.

Gene ID

29881

Swiss Prot

Q9UHC9

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

Niemann Pick C1 Like 1

Clonality

Recombinant

Isotype

IgG

Conjugation

PerCP

Source

KLH conjugated synthetic peptide derived from human NPC1L1

Applications

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

29881

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